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Description
K9 Advantix II Flea, Tick & Mosquito Treatment & Prevention for Large DogsK9 Advantix II Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult
K9 Advantix II Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh to use K9 Advantix II Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Large Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II treatment & prevention protects dogs from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Large
Pet Lifestage
- 7 weeks and older
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.4 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 1
Not Leak Proof
Size: X-Large: 28" x 34"
horrible do not buy! leaks threw and caused a permanent stain and smell. thought it was good but after a week i noticed the smell and lifted up the mat there was complete pee under.
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Reviewed in the United States on April 12, 2026
★★★★★ 5
Great investment
Size: Small: 24" x 24"
It catches the pee that runs off the pad, great investment!!
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Reviewed in the United States on February 12, 2026
★★★★★ 2
It doesn’t stop leaks from the pee pad.
Size: X-Large: 28" x 34"
I’m trying to figure out how not to have leaks occasionally. I’m going to call the company to see if there’s something I should be doing.
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Reviewed in the United States on January 3, 2026
★★★★★ 5
FANTASTIC PAD HOLDER
Size: 28'' X 34'', Size: 28'' X 34''
Amazon Basics Dog Training Pad Holder 28X34.
I'll start out by saying I wasn't too sure about it, when I got it. It is awkward to put the pads in by yourself if your short as on each end the sides have to come up together and it’s big, however, I've done it five times alone now and it’s doable. There was no smell, it arrived in perfect condition. My husband was home and we set it up together, I walked into the bathroom to get a soiled pad I had keep to put on it for her to know what to do came back and she had already used it and she’s only four months old. I love it love it love it, it’s not too big, but it’s her home too, and we have it in the living room where we spend a lot of time as we’re retired. When she gets a little older, we will probably move it to another room, but for now it’s staying there. After she urinates, it goes down to a very pale yellow color I have been able to use one pad for all day, however, she does have a pad in a under bed tote in our master bathroom. We’ve had a few guests over and if she hadn’t used it they didn’t even know what it was. I highly recommend it. I have been using pads in an under the bed tote for over 10 years and this is a welcome audition. You won’t be sorry if you have little ones that go in the house.
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Reviewed in the United States on January 1, 2026
★★★★★ 5
Very easy to use and clean
Size: 22'' X 22''
Saved my pad training with my puppy. It's firm and easy to clean. It holds the pads well for the most part, but sometimes my dog gets a little crazy and it comes out, but I don't think it could be better. Still give a 5-star!
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Reviewed in the United States on May 3, 2026